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Jakubowiak, Andrzej
One or more keywords matched the following items that are connected to Jakubowiak, Andrzej
Item TypeName
Concept Amino Acid Sequence
Concept Base Sequence
Concept Binding Sites
Concept Cell Separation
Concept Drug Synergism
Concept Follicle Stimulating Hormone
Concept Oncogenes
Concept Monoclonal Gammopathy of Undetermined Significance
Concept Organ Size
Concept Molecular Sequence Data
Concept Neoplasm Staging
Concept Sensation Disorders
Concept Peripheral Nervous System Diseases
Concept Sex Characteristics
Concept Spermatids
Concept Population Surveillance
Concept South America
Concept Cohort Studies
Concept Sertoli Cells
Concept Sensitivity and Specificity
Concept Spain
Concept Swine
Concept United States
Concept Hematopoietic Stem Cell Transplantation
Concept Salvage Therapy
Concept Second Messenger Systems
Concept Stem Cell Transplantation
Concept Rats, Sprague-Dawley
Concept Oxidative Stress
Concept Hematopoietic Stem Cell Mobilization
Concept In Situ Hybridization, Fluorescence
Concept Endoplasmic Reticulum Stress
Concept Hypoxia-Inducible Factor 1, alpha Subunit
Concept Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
Concept Sirolimus
Concept Jehovah's Witnesses
Concept Surveys and Questionnaires
Concept Rats, Inbred Strains
Concept Severity of Illness Index
Concept Tandem Mass Spectrometry
Concept Structure-Activity Relationship
Concept Sulfonamides
Concept Propensity Score
Concept High-Throughput Nucleotide Sequencing
Concept Sex Factors
Concept Skin Neoplasms
Concept Spermatocytes
Concept Models, Statistical
Concept Survival Analysis
Concept Open Reading Frames
Concept Genome, Human
Concept Survival Rate
Concept Genes, p53
Concept Granulocyte Colony-Stimulating Factor
Concept Patient Selection
Concept Health Care Surveys
Concept Core Binding Factor Alpha 2 Subunit
Concept Secondary Prevention
Concept Standard of Care
Concept Cell Survival
Concept Drug Administration Schedule
Concept Drug Screening Assays, Antitumor
Concept Follow-Up Studies
Concept Pituitary-Adrenal System
Concept Prospective Studies
Concept Retrospective Studies
Concept Neoplastic Stem Cells
Concept Vaccines, Synthetic
Concept Signal Transduction
Concept Tumor Suppressor Protein p53
Concept Disease-Free Survival
Concept Neurotoxicity Syndromes
Concept Polymorphism, Single Nucleotide
Concept Intracellular Space
Academic Article Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro.
Academic Article The t(8;21) fusion protein, AML1/ETO, transforms NIH3T3 cells and activates AP-1.
Academic Article Differential effects of gonadotropin-releasing hormone (GnRH) pulse frequency on gonadotropin subunit and GnRH receptor messenger ribonucleic acid levels in vitro.
Academic Article Inhibition of the transforming growth factor beta 1 signaling pathway by the AML1/ETO leukemia-associated fusion protein.
Academic Article Molecular biology of leukemia.
Academic Article Effects of cyclic AMP and phorbol ester on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment culture.
Academic Article Effects of recombinant human inhibin and testosterone on gonadotropin secretion and subunit mRNA in superfused male rat pituitary cell cultures stimulated with pulsatile gonadotropin-releasing hormone.
Academic Article Effect of cadmium chloride on transepithelial electrical resistance of Sertoli cell monolayers in two-compartment cultures--a new model for toxicological investigations of the "blood-testis" barrier in vitro.
Academic Article Vectorial secretion of inhibin by immature rat Sertoli cells in vitro: reexamination of previous results.
Academic Article Regulation of transepithelial electrical resistance in two-compartment Sertoli cell cultures: in vitro model of the blood-testis barrier.
Academic Article Tumor cell-selective regulation of NOXA by c-MYC in response to proteasome inhibition.
Academic Article Kinetics of inhibin secretion in static and superfused Sertoli cell cultures in response to follicle-stimulating hormone.
Academic Article A practical guide to achieving and maintaining the best response to lenalidomide in multiple myeloma: roundtable proceedings.
Academic Article Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia.
Academic Article Pulsatile GnRH stimulation increases steady-state mRNA levels for FSHbeta, LHbeta, and alpha subunits in superfused pituitary cell cultures.
Academic Article Conflicts of interest, authorship, and disclosures in industry-related scientific publications.
Academic Article Action kinetics of inhibin in superfused pituitary cells depend on gonadotropin-releasing hormone treatment.
Academic Article Phase II study of thalidomide plus dexamethasone induction followed by tandem melphalan-based autotransplantation and thalidomide-plus-prednisone maintenance for untreated multiple myeloma: a southwest oncology group trial (S0204).
Academic Article Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma.
Academic Article Extended follow-up of a phase 3 trial in relapsed multiple myeloma: final time-to-event results of the APEX trial.
Academic Article A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma.
Academic Article Perifosine plus lenalidomide and dexamethasone in relapsed and relapsed/refractory multiple myeloma: a Phase I Multiple Myeloma Research Consortium study.
Academic Article An open-label, single-arm, phase 2 study of single-agent carfilzomib in patients with relapsed and/or refractory multiple myeloma who have been previously treated with bortezomib.
Academic Article Transferrin secretion in response to different modes of FSH stimulation and cycloheximide in superfused Sertoli cell cultures.
Academic Article Reproductive functions in the adult male rats after prolonged intraventricular administration of corticotropin-releasing factor (CRF).
Academic Article Stimulatory effect of Sertoli cell secretory products on testosterone secretion by purified Leydig cells in primary culture.
Academic Article Effect of germ cells on vectorial secretion of androgen binding protein and transferrin by immature rat Sertoli cells in vitro.
Academic Article Clinical roundtable monograph. Emerging treatment options for relapsed and refractory multiple myeloma.
Academic Article Novel therapies for relapsed/refractory multiple myeloma: how can we improve on "salvage" therapy?--introduction.
Academic Article Management strategies for relapsed/refractory multiple myeloma: current clinical perspectives.
Academic Article An open-label single-arm pilot phase II study (PX-171-003-A0) of low-dose, single-agent carfilzomib in patients with relapsed and refractory multiple myeloma.
Academic Article Study of the dynamics of Sertoli cell secretions in a new superfusion, two-compartment culture system.
Academic Article Perifosine plus bortezomib and dexamethasone in patients with relapsed/refractory multiple myeloma previously treated with bortezomib: results of a multicenter phase I/II trial.
Academic Article Similar effects of inhibin and cycloheximide on gonadotropin release in superfused pituitary cell cultures.
Academic Article Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study.
Academic Article Initial genome sequencing and analysis of multiple myeloma.
Academic Article Alkaline phosphatase variation during carfilzomib treatment is associated with best response in multiple myeloma patients.
Academic Article Superior overall survival of patients with myeloma achieving very good partial response or better to initial treatment with bortezomib, pegylated liposomal doxorubicin, and dexamethasone, predicted after two cycles by a free light chain- and M-protein-based model: extended follow-up of a phase II trial.
Academic Article Culture of rat Sertoli cells isolated with a modified procedure. Morphological identification of cell population and cell reactivity.
Academic Article Phase II trial of combination therapy with bortezomib, pegylated liposomal doxorubicin, and dexamethasone in patients with newly diagnosed myeloma.
Academic Article Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies.
Academic Article Lenalidomide, bortezomib, pegylated liposomal doxorubicin, and dexamethasone in newly diagnosed multiple myeloma: a phase 1/2 Multiple Myeloma Research Consortium trial.
Academic Article Evaluation of HLA expression on gametogenic cells isolated from human testis.
Academic Article An open-label, single-arm, phase 2 (PX-171-004) study of single-agent carfilzomib in bortezomib-naive patients with relapsed and/or refractory multiple myeloma.
Academic Article A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma.
Academic Article Treatment outcomes in patients with relapsed and refractory multiple myeloma and high-risk cytogenetics receiving single-agent carfilzomib in the PX-171-003-A1 study.
Academic Article Evolving strategies in the initial treatment of multiple myeloma.
Academic Article Introduction: recent advances in the understanding and management of multiple myeloma.
Academic Article A phase 2 trial of lenalidomide, bortezomib, and dexamethasone in patients with relapsed and relapsed/refractory myeloma.
Academic Article Pomalidomide alone or in combination with low-dose dexamethasone in relapsed and refractory multiple myeloma: a randomized phase 2 study.
Academic Article Current strategies for treatment of relapsed/refractory multiple myeloma.
Academic Article Monoclonal antibodies in the treatment of multiple myeloma.
Academic Article Evolution of carfilzomib dose and schedule in patients with multiple myeloma: a historical overview.
Academic Article Phase 1 study of twice-weekly ixazomib, an oral proteasome inhibitor, in relapsed/refractory multiple myeloma patients.
Academic Article Carfilzomib, lenalidomide, and low-dose dexamethasone in elderly patients with newly diagnosed multiple myeloma.
Academic Article Targeting deubiquitinase activity with a novel small-molecule inhibitor as therapy for B-cell malignancies.
Academic Article Serum free light chain reduction correlates with response and progression-free survival following carfilzomib therapy in relapsed/refractory multiple myeloma.
Academic Article Elotuzumab in combination with lenalidomide and dexamethasone in patients with relapsed multiple myeloma: final phase 2 results from the randomised, open-label, phase 1b-2 dose-escalation study.
Academic Article Phase I Study of the Novel Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (MLN4924) in Patients with Relapsed/Refractory Multiple Myeloma or Lymphoma.
Academic Article Synergistic Myeloma Cell Death via Novel Intracellular Activation of Caspase-10-Dependent Apoptosis by Carfilzomib and Selinexor.
Academic Article Daratumumab monotherapy in patients with treatment-refractory multiple myeloma (SIRIUS): an open-label, randomised, phase 2 trial.
Academic Article Phase 1 study of marizomib in relapsed or relapsed and refractory multiple myeloma: NPI-0052-101 Part 1.
Academic Article Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM.
Academic Article Anti-myeloma activity of MELK inhibitor OTS167: effects on drug-resistant myeloma cells and putative myeloma stem cell replenishment of malignant plasma cells.
Academic Article Carfilzomib significantly improves the progression-free survival of high-risk patients in multiple myeloma.
Academic Article A phase 1 dose-escalation study of filanesib plus bortezomib and dexamethasone in patients with recurrent/refractory multiple myeloma.
Academic Article Cost-effectiveness of adding carfilzomib to lenalidomide and dexamethasone in relapsed multiple myeloma from a US perspective.
Academic Article Current approaches to the initial treatment of symptomatic multiple myeloma.
Academic Article Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy.
Academic Article Phase II study of lenalidomide (Len), bortezomib (Bz), and dexamethasone (Dex) in patients (pts) with relapsed or relapsed and refractory multiple myeloma (MM).
Academic Article Health-Related Quality-of-Life Results From the Open-Label, Randomized, Phase III ASPIRE Trial Evaluating Carfilzomib, Lenalidomide, and Dexamethasone Versus Lenalidomide and Dexamethasone in Patients With Relapsed Multiple Myeloma.
Academic Article Safety and efficacy of lenalidomide (Len), bortezomib (Bz), and dexamethasone (Dex) in patients (pts) with newly diagnosed multiple myeloma (MM): A phase I/II study.
Academic Article Carfilzomib, lenalidomide, and dexamethasone in patients with relapsed multiple myeloma categorised by age: secondary analysis from the phase 3 ASPIRE study.
Academic Article Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells.
Academic Article Carfilzomib-lenalidomide-dexamethasone vs lenalidomide-dexamethasone in relapsed multiple myeloma by previous treatment.
Academic Article Cardiovascular events during carfilzomib therapy for relapsed myeloma: practical management aspects from two case studies.
Academic Article Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma.
Academic Article Cost-effectiveness of carfilzomib plus dexamethasone compared with bortezomib plus dexamethasone for patients with relapsed or refractory multiple myeloma in the United States.
Academic Article Daratumumab plus Bortezomib, Melphalan, and Prednisone for Untreated Myeloma.
Academic Article Comparative proteomic profiling of sera from patients with refractory multiple myeloma reveals potential biomarkers predicting response to bortezomib-based therapy.
Academic Article Reframing the Value of Treatments for Relapsed/Refractory Multiple Myeloma.
Academic Article Improvement in Overall Survival With Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma.
Academic Article Prognostic Validation of SKY92 and Its Combination With ISS in an Independent Cohort of Patients With Multiple Myeloma.
Academic Article Combining carfilzomib and panobinostat to treat relapsed/refractory multiple myeloma: results of a Multiple Myeloma Research Consortium Phase I Study.
Academic Article Daratumumab plus carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma.
Academic Article Phase 1 study of selinexor plus carfilzomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.
Academic Article A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia.
Academic Article Results from a multidisciplinary clinic guided by geriatric assessment before stem cell transplantation in older adults.
Academic Article Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models.
Academic Article Overall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial.
Academic Article Regulatory T-cell depletion in the setting of autologous stem cell transplantation for multiple myeloma: pilot study.
Academic Article First-in-Human Phase I Study of ABBV-838, an Antibody-Drug Conjugate Targeting SLAMF7/CS1 in Patients with Relapsed and Refractory Multiple Myeloma.
Academic Article Developments in continuous therapy and maintenance treatment approaches for patients with newly diagnosed multiple myeloma.
Academic Article Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses.
Academic Article Integrated safety profile of selinexor in multiple myeloma: experience from 437 patients enrolled in clinical trials.
Academic Article Selinexor-based regimens for the treatment of myeloma refractory to chimeric antigen receptor T cell therapy.
Academic Article Comparative Efficacy of Bortezomib, Melphalan, and Prednisone (VMP) With or Without Daratumumab Versus VMP Alone in the Treatment of Newly Diagnosed Multiple Myeloma: Propensity Score Matching of ALCYONE and VISTA Phase III Studies.
Academic Article Daratumumab, lenalidomide, bortezomib, and dexamethasone for transplant-eligible newly diagnosed multiple myeloma: the GRIFFIN trial.
Academic Article Clinician attitudes and practices toward measurable residual disease in multiple myeloma.
Academic Article Impact of an Oncology Clinical Pharmacist Specialist in an Outpatient Multiple Myeloma Clinic.
Academic Article Corneal Epithelial Findings in Patients with Multiple Myeloma Treated with Antibody-Drug Conjugate Belantamab Mafodotin in the Pivotal, Randomized, DREAMM-2 Study.
Academic Article Carfilzomib, lenalidomide, and dexamethasone plus transplant in newly diagnosed multiple myeloma.
Academic Article Racial differences in treatment and outcomes in multiple myeloma: a multiple myeloma research foundation analysis.
Academic Article International harmonization in performing and reporting minimal residual disease assessment in multiple myeloma trials.
Academic Article Correction to: Corneal Epithelial Findings in Patients with Multiple Myeloma Treated with Antibody-Drug Conjugate Belantamab Mafodotin in the Pivotal, Randomized, DREAMM-2 Study.
Academic Article Sex differences in outcomes in multiple myeloma.
Academic Article Recommendations and outcomes from a geriatric assessment guided multidisciplinary clinic prior to autologous stem cell transplant in older patients.
Academic Article Bloodless chimeric antigen receptor (CAR) T-cell therapy in Jehovah's Witnesses.
Academic Article Measurable residual disease assessed by mass spectrometry in peripheral blood in multiple myeloma in a phase II trial of carfilzomib, lenalidomide, dexamethasone and autologous stem cell transplantation.
Academic Article Health-related quality of life in patients with newly diagnosed multiple myeloma ineligible for stem cell transplantation: results from the randomized phase III ALCYONE trial.
Academic Article Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study.
Academic Article Sustained minimal residual disease negativity in newly diagnosed multiple myeloma and the impact of daratumumab in MAIA and ALCYONE.
Academic Article Knowing the unknowns in high risk multiple myeloma.
Academic Article Phase 2 study of venetoclax plus carfilzomib and dexamethasone in patients with relapsed/refractory multiple myeloma.
Academic Article Carfilzomib, dexamethasone, and daratumumab versus carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma (CANDOR): updated outcomes from a randomised, multicentre, open-label, phase 3 study.
Academic Article Incidence and management of CAR-T neurotoxicity in patients with multiple myeloma treated with ciltacabtagene autoleucel in CARTITUDE studies.
Academic Article Phase 1 study of CART-ddBCMA for the treatment of subjects with relapsed and refractory multiple myeloma.
Academic Article Daratumumab Improves Depth of Response and Progression-free Survival in Transplant-ineligible, High-risk, Newly Diagnosed Multiple Myeloma.
Academic Article Efficacy and safety of carfilzomib-lenalidomide-dexamethasone in newly diagnosed multiple myeloma: pooled analysis of four single-arm studies.
Academic Article Ciltacabtagene Autoleucel, an Anti-B-cell Maturation Antigen Chimeric Antigen Receptor T-Cell Therapy, for Relapsed/Refractory Multiple Myeloma: CARTITUDE-1 2-Year Follow-Up.
Academic Article Antibody and T cell responses to COVID-19 vaccination in patients receiving anticancer therapies.
Academic Article Clinician survey regarding measurable residual disease-guided decision-making in multiple myeloma.
Academic Article Elotuzumab and Weekly Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Without Transplant Intent: A Phase 2 Measurable Residual Disease-Adapted Study.
Academic Article Longitudinal Real-World Neuropathy and Patient-Reported Outcomes With Bortezomib and Lenalidomide in Newly Diagnosed Multiple Myeloma.
Academic Article Stem Cell Mobilization Yields with Daratumumab- and Lenalidomide-Containing Quadruplet Induction Therapy in Newly Diagnosed Multiple Myeloma: Findings from the MASTER and GRIFFIN Trials.
Academic Article Patient Perceptions Regarding Ciltacabtagene Autoleucel Treatment: Qualitative Evidence From Interviews With Patients With Relapsed/Refractory Multiple Myeloma in the CARTITUDE-1 Study.
Academic Article Carfilzomib, lenalidomide, and dexamethasone or lenalidomide alone as maintenance therapy after autologous stem-cell transplantation in patients with multiple myeloma (ATLAS): interim analysis of a randomised, open-label, phase 3 trial.
Academic Article Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma.
Academic Article Body Mass Index and Overall Survival of Patients with Newly Diagnosed Multiple Myeloma.
Academic Article Adjusted comparison of outcomes between patients from CARTITUDE-1 versus multiple myeloma patients with prior exposure to proteasome inhibitors, immunomodulatory drugs and anti-CD38 antibody from the prospective, multinational LocoMMotion study of real-world clinical practice.
Academic Article Health-related quality of life in patients given ciltacabtagene autoleucel for relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b-2, open-label study.
Academic Article Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma.
Academic Article A phase I study of selinexor combined with weekly carfilzomib and dexamethasone in relapsed/refractory multiple myeloma.
Academic Article Phase 1/2 study of carfilzomib, pomalidomide, and dexamethasone with and without daratumumab in relapsed multiple myeloma.
Academic Article A plain language summary of daratumumab plus lenalidomide/bortezomib/dexamethasone in transplant-eligible Black patients with newly diagnosed multiple myeloma in the GRIFFIN study.
Concept Signaling Lymphocytic Activation Molecule Family
Concept Smoldering Multiple Myeloma
Concept Myeloid Cell Leukemia Sequence 1 Protein
Academic Article Extrapolation of Survival Data Using a Bayesian Approach: A Case Study Leveraging External Data from Cilta-Cel Therapy in Multiple Myeloma.
Academic Article Polyclonal immunoglobulin recovery in patients with newly diagnosed myeloma receiving maintenance therapy after autologous haematopoietic stem cell transplantation with either carfilzomib, lenalidomide and dexamethasone or lenalidomide alone: Subanalysis of the randomized phase 3 ATLAS trial.
Academic Article Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial.
Academic Article Optimization of Metabolic Tumor Volume as a Prognostic Marker in CAR T-Cell Therapy for Aggressive Large B-cell NHL.
Academic Article Post hoc analysis of daratumumab plus lenalidomide, bortezomib and dexamethasone in Black patients from final data of the GRIFFIN study.
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